Annexin V-FITC Early Apoptosis Detection Kit

Annexin V-FITC Early Apoptosis Detection Kit

Cat. No.: DAA-001059

Size: 1 x 96 tests Size: 10 x 96 tests Size: Customer Size
Product Information
Product Name Annexin V-FITC Early Apoptosis Detection Kit
Description The Annexin V-FITC Early Apoptosis Detection Kit enables researchers to identify early apoptotic cells within a cell population. Annexin V-FITC conjugated protein binds to cell surfaces expressing phosphatidylserine, an early apotosis marker. Cells stained with propidium iodide (PI), a non-cell-permeable DNA dye, indicate necrotic cells. Cells stained with both PI and annexin V-FITC demonstrate later stage apoptosis and early necrosis. This kit provides enough reagent to perform 100 assays, based on a 250 μl assay volume.
Component Annexin V-FITC Conjugate; 10X Annexin V Binding Buffer; Propidium Iodide (PI) Solution
Target Information
Target Name ANXA5
UniProt No. P08758
Gene ID 308
Target Description Annexin V belongs to the annexin family of proteins consisting of over 160 members. All annexin family members share the same charactersistic of Ca2+-dependent binding to negatively charged phospholipid surfaces. During early apoptosis, phosphatidylserine (PS) is translocated from the cytosolic side of the plasma membrane to the cellular surface. This translocation exposes PS to the extracellular environment with the plasma membrane left intact. Annexin V protein demonstrates high affinity, specificity, and sensitivity for PS and can be used as a marker of early apoptosis. In order to rule out "leaky" necrotic cells, annexin V must be used in tandem with reagents that determine the integrity of the cell membrane, such as propidium iodide.
Alternative Names Anchorin CII; Annexin V; Annexin-5; Calphobindin I (CPB-I); Endonexin II; Lipocortin V; Placental anticoagulant protein 4 (PP4); Placental anticoagulant protein I (PAP-I); Thromboplastin inhibitor; Vascular anticoagulant-alpha (VAC-alpha)
Shipping & Storage
Sipping Shipping on dry ice.
Storage Store at -20°C. Please refer to protocols.
All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.
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