C57BL/6J-Cckbrem1 Mouse

C57BL/6J-Cckbrem1 Mouse

Cat. No.: DMM-001010

Status Age Sex
  • Live Mouse
  • Frozen Embryo
  • 4 weeks
  • 12 weeks
  • Customized Age
  • Male
  • Female
Product Overview
Model Description Exon 3 of Cckbr gene was deleted to generate Cckbr knockout mice.
Strain Name C57BL/6J-Cckbrem1
Background Strain C57BL/6J
SPF Yes
Research Application This gene encodes a G-protein coupled receptor for gastrin and cholecystokinin (CCK); regulatory peptides of the brain and gastrointestinal tract. This protein is a type B gastrin receptor; which has a high affinity for both sulfated and nonsulfated CCK analogs and is found principally in the central nervous system and the gastrointestinal tract. A misspliced transcript variant including an intron has been observed in cells from colorectal and pancreatic tumors.
Target Information
Target Name Cckbr
Synonyms CCK2R, CCK-BR, CCK2-R, CCKR-2
Gene ID 12426
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