db/db Mouse

db/db Mouse

Cat. No.: DMM-001005

Status Age Sex
  • Live Mouse
  • Frozen Embryo
  • 4 weeks
  • 12 weeks
  • Customized Age
  • Male
  • Female
Product Overview
Model Description An intronic G-to-T transversion in this allele created a donor splice site that causes abnormal splicing and the inclusion of 106 nt of intronic sequence in the transcript, leading to premature termination of the long cellular domain of the Ob-Rb splice form and loss of its signal transducing function.
Strain Name B6.BKS(D)-Leprdb/J
Background Strain B6.BKS
SPF Yes
Research Application Leptin resistance; insulin resistance; obesity; and type 2 diabetes.
Target Information
Target Name Lepr
Synonyms Leprb, LEPROT, leptin receptor gene-related protein, Modb1, obese-like, obl, Obr, OB-RGRP
Gene ID 16847
All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.
Related Products
logo
Contact Info
Copyright © Ace Metabolism. All Rights Reserved.
Top