GDM Mouse Models

Gestational diabetes is a type of diabetes that occurs during pregnancy. Hormones produced by the placenta can make it harder for the body to use insulin effectively, resulting in high blood sugar levels. Gestational diabetes usually develops during the second or third trimester of pregnancy and often goes away after the baby is born. However, women who have had gestational diabetes are at increased risk of developing type 2 diabetes later in life.

HFD-GDM C57BL/6 Mice HFD-GDM mice are pregnant C57BL/6 mice fed a high-fat diet and develop insulin resistance, impaired glucose tolerance, and hyperglycemia.
STZ-induced Pregnant Mice STZ-induced diabetic pregnant mice also develop gestational diabetes due to beta-cell dysfunction and insulin resistance.
ob/ob Mice This strain is obese and genetically prone to developing type 2 diabetes. These mice have been used to study the effects of maternal obesity on gestational diabetes and fetal development

Our mouse models of gestational diabetes can be used to investigate potential treatments for the condition, such as dietary interventions or drug therapies. They can also be used to study the long-term effects of gestational diabetes on offspring and to explore the mechanisms by which maternal glucose metabolism affects fetal development.

Besides, we provide customized mouse model generation service for gestational diabetes study with guaranteed quality and efficiency. Just in case you couldn't find what you need, please feel free to contact us and get started with our professional one-stop service.

GDM Mouse Models for Diabetes Research
  • Target Name: Pdcd4
  • Backgrounds: B6.129S6
  • Target Name: Cdkal1
  • Backgrounds: C57BL/6J
  • Target Name: Gck
  • Backgrounds: C57BL/6J
C57BL/6J-Gad2em1 Mouse (DMM-001166)
  • Target Name: Gad2
  • Backgrounds: C57BL/6J
Adipor1-KO Mouse (DMM-001220)
  • Target Name: Adipor1
  • Backgrounds: C57BL/6JSmoc
Adipor1-Flox Mouse (DMM-001221)
  • Target Name: Adipor1
  • Backgrounds: C57BL/6JSmoc
Met-Flox Mouse (DMM-001222)
  • Target Name: Met
  • Backgrounds: C57BL/6JSmoc
Met-2A-CreERT2 Mouse (DMM-001223)
  • Target Name: Met
  • Backgrounds: C57BL/6JSmoc
Met-KO Mouse (DMM-001224)
  • Target Name: Met
  • Backgrounds: C57BL/6JSmoc
hMET Mouse (DMM-001225)
  • Target Name: Met
  • Backgrounds: C57BL/6JSmoc
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