Human TSC1 knockout A549 cell line

Human TSC1 knockout A549 cell line

Cat. No.: DCL-001023

Size: 1 × 106 cells/vial Size: Customer Size
Product Information
Parental A549
Organism Human
Tissue Lung
Target Name TSC1
Cell Type Epithelial cells
Gender Male
UniProt No. Q92574
Gene ID 7248
Gene Description In complex with TSC2, inhibits the nutrient-mediated or growth factor-stimulated phosphorylation of S6K1 and EIF4EBP1 by negatively regulating mTORC1 signaling. Seems not to be required for TSC2 GAP activity towards RHEB. Implicated as a tumor suppressor. Involved in microtubule-mediated protein transport, but this seems to be due to unregulated mTOR signaling.
Format Frozen
Growth Properties Adherent
Shipping & Storage
Shipping Cryopreserved on dry ice.
Storage Instructions Store in liquid nitrogen.
Storage Buffer/Media 8.7% Dimethylsulfoxide, 2% Cellulose, methyl ether
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