NONcNZO10/LtJ Mouse

NONcNZO10/LtJ Mouse

Cat. No.: DMM-001007

Status Age Sex
  • Live Mouse
  • Frozen Embryo
  • 4 weeks
  • 12 weeks
  • Customized Age
  • Male
  • Female
Product Overview
Model Description NONcNZO10/LtJ is a recombinant congenic strain to model human obesity-induced Type 2 diabetes and Metabolic Syndrome. Type 2 diabetes in males of this strain results from polygenic interactions producing a moderate obesity rather than the massive obesity elicited by mutations in the leptin/leptin receptor axis. Unlike mice with monogenic obesity syndromes, NONcNZO10/LtJ males do not exhibit hypercorticism, are not hyperphagic, and show no obvious thermoregulatory defects.
Strain Name NONcNZO10/LtJ
Background Strain NON/Lt
SPF Yes
Research Application Diabetes
All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.
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