ob/ob Mouse

ob/ob Mouse

Cat. No.: DMM-001006

Status Age Sex
  • Live Mouse
  • Frozen Embryo
  • 4 weeks
  • 12 weeks
  • Customized Age
  • Male
  • Female
Product Overview
Model Description Sequencing of RT-PCR products revealed a nonsense mutation in arginine codon 105 resulting from a C-to-T point mutation. The 16 kDa leptin protein, expressed predominantly in adipose tissue of normal mice, is missing from homozygous mutant mice
Strain Name B6.Cg-Lepob/J
Background Strain B6.Cg
SPF Yes
Research Application Diabetes
Target Information
Target Name Lep
Synonyms Leptin
Gene ID 16846
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